Mainstream culture had some very different ideas about drugs at different points in history; cocaine was once a popular over-the-counter drug prescribed for everything from shyness to toothaches until 1914, while amphetamines -- or "pep" as they were sometimes called -- were recommended for depression and weight loss, and sold over the counter until 1971. At one point in time even Mickey Mouse got in on the action, promoting the sale of speed with Goofy in a 1951 comic for an amphetamine product called Peppo that kids could collect for 15 cents and a Wheaties cereal box top.

Sure, it was funny when Curious George got into the ether, but it's hard to top Goofy and Mickey having adventures while strung out on crank. Check out the full comic after the jump.